黄　蓉

姓名：黄蓉

职称：副教授

学科专业：化学生物学

研究方向：药物化学生物学

电子邮箱：ronghuang@mail.scuec.edu.cn

教育及工作经历

2022.03-至今：中南民族大学，药学院，副教授，硕士生导师；

2015.04-2022.03：中南民族大学，药学院，讲师，硕士生导师；

2013.09-2014.09，英国剑桥大学化学系,公派联合培养博士生；

2009.09-2014.12：武汉大学化学与分子科学学院，获理学博士学位；

2005.09-2009.06：武汉大学化学与分子科学学院，获理学学士学位；

教学工作

累计承担多门本科生课程教学工作，主要包括《生物化学（药）》理论课及实验课、《生物有机化学》、《药学分子生物学》等；获批2项校级教研项目，1项校级思政项目，发表教研论文3篇，参编教材1部。目前已指导50多名本科生完成毕业论文设计，其中2名本科生获校级优秀学士学位论文；指导本科生团队获“全国大学生生命科学竞赛”国家级一等奖1项，二等奖1项，三等奖2项；指导“大学生创新训练计划”国家级3项，省级2项。

部分获奖及荣誉称号

2022-2024年武汉市第三批中小微企业“科技副总”

2021年武汉市“巾帼文明岗”（负责人）

2021年中南民族大学“先进青年文明号”（负责人）

2024年中南民族大学“五四青年教工先锋”

2023年中南民族大学“优秀党务工作者”

2020年中南民族大学第六届“优秀女教工”

2015年中南民族大学助教试讲竞赛二等奖

2019和2021年中南民族大学“先进基层工会工作者”

并多次获评中南民族大学“创新优秀指导教师”、“挑战杯”大学生创业计划竞赛“优秀指导老师”、“优秀学士学位论文指导老师”等荣誉称号。

主持或参加科研及教学项目

1. 国家自然科学基金面上项目，22377152，基于真菌活性天然产物的BacPROTAC分子构建及其清除MRSA生物被膜的研究，2024/01-2027/12，50万元，在研，主持

2. 国家自然科学基金青年项目，21502239，靶向转录因子FOXM1的抑制剂设计、筛选及其对转录机制调控的研究，2016/01-2018/12，25.2万元，已结题，主持

3. 中央高校基本科研业务费专项资金项目，CZQ21017，天然来源的混源萜类化合物调控氧化应激-炎症级联反应的机制研究，2021/04-2023/04, 5万元，结题，主持

4. 中央高校基本科研业务费专项资金项目，CZQ19013，靶向PD-1/PD-L1的小分子抑制剂筛选及其抗肿瘤免疫活性研究，2019/03-2021/03, 4万元，结题，主持

5. 中南民族大学教学研究项目，JYX18050，生物有机化学专题模块教学探索，2万元，结题，主持

6. 中南民族大学教学研究项目（课程思政示范课程），KCSZX21016，生物有机化学，2万，在研，主持

7. 湖北省技术创新计划项目，2023BCB062，道地药材潜半夏产地加工与炮制一体化技术产业化研发与应用，2023/01-2025/12, 200万元，在研，主要参与人

代表性研究成果和学术奖励情况

1.Rong Huang^#, Chuang Cai^#, Wei-Wei Cheng, Yin-Jia Cheng, Wen-Long Liu, Yi-Han Ma, Ai-Qing Zhang, and Si-Yong Qin*, Injectable Peptide Liquid Crystal Hydrogel with Hierarchical Microstructure Directs Myoblast Alignment and Potentiates Muscle Functional Recovery,Advanced Functional Materials, 2025, e00204. (SCI一区Top, Nature指数收录期刊,IF 19)

2.Rong Huang^#, Wen-Yu Zhang^#, Yue-Qi Hu, Jun-Jie Xu, Zhi-Hui Dong, Ji-Kai Liu*, Li Zhou*,Houttuynia cordataPolysaccharides Ameliorate Atopic Dermatitis in Mice through Modulation of Skin Immune Barrier and Lipid Metabolism,International Journal of Biological Macromolecules,2025, 314:144264. (SCI二区Top, IF 8.5)

3. Ding-Yi Zhang^#, Meng-Xi Wang^#, Chuang Cai^#, Wei-Wei Cheng, Yin-Jia Cheng, Wen-Long Liu,Rong Huang^*, Ai-Qing Zhang, Si-Yong Qin^*, Bacterial Membrane-Anchored Lipopeptide/Mxene Nanoplatform for Tri-Modal Therapy Toward Bacteria-Infected Diabetic Wound,Biomaterials Advances, 2025, 175:214324. (SCI二区Top, IF 6)

4. Hui Guo^#, Yu-Qi Tian^#, Xing Wu^#, Liang Tu, Ji-Kai Liu^*, Yong-Sheng Zheng^*,Rong Huang^*, Efficient Assembly and Anti-Tumor Evaluation of Novel Polycyclic [1,2-a]-Fused Indoles,Bioorganic Chemistry, 2024, 146: 107289. (SCI二区Top, IF 5.1)

5. Qian Chen^#, Zhi-Hui Dong^#, Xue-Di Yao^#, Huan Sun, Xin Pan*, Jikai Liu* andRong Huang*, Bactericidal and Biofilm Eradication Efficacy of a Fluorinated Benzimidazole Derivative, TFBZ, against Methicillin-ResistantStaphylococcus aureus,Frontiers in Pharmacology, 2024, 1342821. (SCI二区, IF 4.4)

6. Jia-Qi Feng^#, Xiang Tiana^#, Rui-Ge Cao^#, Yong-Xiu Li, Wen-Long Liu,Rong Huang^*, Si-Yong Qin^*, Ai-Qing Zhang^*, Yin-Jia Cheng^*, An AIE-Based Theranostic Nanoplatform for Enhanced Colorectal Cancer Therapy: Real-Time Tumor-Tracking and Chemical-Enhanced Photodynamic Therapy,Chinese Chemical Letters, 2024, 109657.(SCI一区Top, IF 9.1)

7. Ding-Yi Zhang^#, Rui-Ge Cao^#, Yin-Jia Cheng, Wen-Long Liu,Rong Huang^*, Ai-Qing Zhang^*, Si-Yong Qin^*, Programming Lipopeptide Nanotherapeutics for Tandem Treatment of Postsurgical Infection and Melanoma Recurrence,Journal of Controlled Release, 2023, 362: 565. (SCI一区Top, IF 10.8)

8.Rong Huang^#, Jia-Xu Yao^#, Li Zhou^*, Xiang Li, Jin-Rui Zhu, Yue-Qi Hu and Ji-Kai Liu^*, Protective Effect and Mechanism Insight of Purified Antarctic Krill Phospholipids against Mice Ulcerative Colitis Combined with Bioinformatics,Natural Products and Bioprospecting, 2023, 13:11.(SCI二区, IF 4.7)

9. Qi-Hang Yu^#,Rong Huang^#, Kai-Yue Wu^#, Xiao-Le Han, Yin-Jia Chen, Wen-Long Liu, Ai-Qing Zhang, Si-Yong Qin^*, Infection-Activated Lipopeptide Nanotherapeutics with Adaptable Geometrical Morphology for in Vivo Bacterial Ablation,Acta Biomaterialia,2022, 154: 359.（SCI一区Top,IF 10.3）

10.Rong Huang^#, Qi-Hang Yu^#, Xue-Di Yao^#, Wen-Long Liu, Yin-Jia Chen, Yi-Han Ma, Ai-Qing Zhang, Si-Yong Qin^*, Self-Deliverable Peptide-Mediated and Reactive-Oxygen-Species-Amplified Therapeutic Nanoplatform for Highly Effective Bacterial Inhibition,ACS Applied Materials & Interfaces, 2022, 14: 159. (SCI二区Top, IF 9.2)

11. Li Zhou^#, Xing Wu^#, Fu Yang, Ming-Hao Zhang,Rong Huang^*, Ji-Kai Liu^*, Characterization of Molecular Species and Anti-Inflammatory Activity of Purified Phospholipids from Antarctic Krill Oil,Marine Drugs, 2021, 19(3): 124. (SCI二区, IF 5.1)

12. Rui-Ge Cao^#, Xing Wu^#, Hui Guo, Xin Pan,Rong Huang^*, Gang-Qiang Wang^*, Ji-Kai Liu*, Naringin Exhibited Therapeutic Effects against DSS-Induced Mice Ulcerative Colitis in Intestinal Barrier–Dependent Manner,Molecules,2021, 26(21): 6604.(SCI二区, IF 4.4)

13. Ting-Ting Yao, Xiao-Wei Xu^*,Rong Huang^*, Recent Advances about the Applications of Click Reaction in Chemical Proteomics,Molecules, 2021, 26(17): 5368.(SCI二区,IF 4.4)

14. Hui-Xiang Yang, Jin-Tao Ma, Juan He, Zheng-Hui Li,Rong Huang^*, Tao Feng^*, Ji-Kai Liu*, Pardinumones A−D: Antibacterial Polyketide−Amino Acid Derivatives from the Mushroom Tricholoma Pardinum,ACS Omega, 2021, 6: 25089.(IF 3.5)

15.Rong Huang^*, Xian-Dong Zhang, Xing Wu, Ji-Kai Liu^*, β-Carboline-Based pH Fluorescent Probe and Its Application for Monitoring Enzymatic Ester Hydrolysis,Chemistry & Biodiversity, 2021, 18(1): e2000829.(IF 2.4)

16. Zhou Zhao^#, Feng Lin^#, Hui Ye,Rong Huang^*, Xiao-Wei Xu^*, Effects of Modified-Guanosine on the Stability of G-Triplex,Tetrahedron Letters, 2016, 57(48): 5321.(IF 2.4)

17.Rong Huang^#,Jia-Qi Wang^#,Wu-Xiang Mao,Bo-Shi Fu,Xi-Wen Xing, GeGuo, Xiang Zhou^*, A Novel Combined Bisulfite UDG Assay for Selective 5-Methylcytosine Detection,Talanta,2013,117(0):445.(IF 6.0)

18. Jun Wu^#,RongHuang^#, Chang-Cheng Wang, Wen-Ting Liu, Jia-Qi Wang, Xiao-Cheng Weng, Tian Tian, XiangZhou^*, Thiol-Inducible Direct Fluorescence Monitoring of Drug Release,Organic & Biomolecular Chemistry, 2013,11(4): 580.(IF 3.8)

19.Rong Huang^#,Sheng-Yong Yan^#, Xiao-Long Zheng, Feng-Ling Luo, Ming-Gang Deng, Bo-Shi Fu, Yi-Jie Xiao, Xi Zhao, Xiang Zhou^*,Development of a pH-Activatable Fluorescent Probe and Its Application for Visualizing Cellular pH Change,Analyst,2012,137(19):4418.(IF 4.6)

20.Rong Huang^#,Xiao-Long Zheng^#, Chang-Cheng Wang, Ren-Yi Wu, Sheng-Yong Yan, Jia-Qi Yuan, Xiao-Cheng Weng, Xiang Zhou^*, Reaction-Based Two-Photon Fluorescent Probe for Turn-On Mercury (II) Sensing and Imaging in Live Cells,Chemistry-An Asian Journal,2012,7(5):915.(IF 4.5)

21. Sheng-Yong Yan^#,RongHuang^#, Chang-ChengWang, Yi-Min Zhou, Jia-Qi Wang, Bo-Shi Fu, Xiao-Cheng Weng, XiangZhou^*,A Two-photon Fluorescent Probe for Intracellular Detection of Tyrosinase Activity,Chemistry-An Asian Journal,2012, 7, (12): 2782.(IF 4.5)

22. Sheng-Yong Yan^#,Rong Huang^#,Yang-Yang Zhou, Ming Zhang, Ming-Gang Deng, Xiao-Lin Wang, Xiao-Cheng Weng, Xiang Zhou^*,Aptamer-Based Turn-On Fluorescent Four-Branched Quaternary Ammonium Pyrazine Probe for Selective Thrombin Detection,Chemical Communications,2011,47(4):1273.(IF 6.2)

23. 黄蓉，刘吉开，姚雪迪，孙焕，苯并咪唑类化合物的新应用，2021-11-19，中国发明专利，ZL 202111399570.9.

24. 黄蓉，郑永胜，郭辉，涂亮，刘吉开，一种高非对映选择性多环吲哚类化合物及其合成方法和应用，2022-09-30，中国发明专利，ZL 202211212324.2.

25. 黄蓉，董智慧，刘吉开，袁海军，熊伟，半夏多糖在制备缓解特应性皮炎药物中的应用，2024-02-02，中国发明专利，ZL 202410158632.4.